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  • Sickle Cell Disease - What Is Sickle Cell Disease? - NHLBI, NIH
    Sickle cell disease — also called sickle cell anemia — is a group of inherited disorders that affect hemoglobin , the major protein that carries oxygen in red blood cells Normally, red blood cells are disc-shaped and flexible so they can move easily through the blood vessels
  • Sickle Cell Disease - Causes and Risk Factors - NHLBI, NIH
    Sickle cell disease is sometimes called sickle cell anemia People have sickle cell trait if they inherit a copy of the sickle cell gene from one parent and a copy of the gene for normal hemoglobin, called hemoglobin A, from the other People who have sickle cell trait make about 60% normal hemoglobin (hemoglobin A) and 40% sickle hemoglobin
  • Sickle Cell Disease - Treatment - NHLBI, NIH
    Hydroxyurea is an oral medicine that is frequently prescribed to help treat sickle cell disease Hydroxyurea is an oral medicine that can reduce sickling of red blood cells and help prevent serious symptoms of sickle cell disease, including pain crises Healthcare providers usually prescribe daily hydroxyurea for infants as young as 9 months
  • Sickle Cell Disease - Symptoms - NHLBI, NIH
    Serious symptoms of sickle cell disease are emergencies and need treatment right away Seek care or call 9-1-1 if you or someone else is experiencing: Severe pain A serious pain event is sometimes called a “pain crisis,” “sickle cell crisis,” or “vaso-occlusive crisis ” Most people with sickle cell disease have this often-serious pain
  • Sickle Cell Disease Fact Sheet - NHLBI, NIH
    Sickle cell disease (SCD) is the most common inherited blood disorder in the United States In this fact sheet, learn about the causes, signs and symptoms, diagnosis, and treatment of SCD Print Length:
  • How Sickle Cell Disease May Affect Your Health - NHLBI, NIH
    In sickle cell disease, it can cause the bone marrow to stop producing new red cells for a while, leading to severe anemia Splenic sequestration crises : When red blood cells get trapped in the spleen, fewer are available to circulate in the blood
  • Sickle Cell Disease Milestones in Research and Clinical Progress
    term “sickle cell anemia” is coined “The shape of the reds was very irregular, but what especially attracted attention was the large number of thin, elongated, sickle-shaped, and crescent-shaped forms ” — Dr James B Herrick 1933 Scientists include 2,500 African Americans in a study that shows sickle cell trait and sickle cell
  • SICKLE CELL DISEASE - NHLBI, NIH
    SICKLE CELL DISEASE Sickle cell disease (SCD) is the most common inherited blood disorder in the United States People with SCD are born with it This disease gets its name from the abnormal crescent or “sickle” shape that some red blood cells develop Because of this shape and other abnormalities, sickled
  • Sickle Cell Disease - Diagnosis - NHLBI, NIH
    Newborn screening programs also find out whether your baby has sickle cell trait and is a carrier of the sickle cell gene If this is the case, genetic counseling will be offered When a child has sickle cell trait or sickle cell disease, their future siblings or your child's future children may be a carrier of the sickle cell gene
  • Sickle Cell Disease Research - NHLBI, NIH
    The National Institutes of Health (NIH) has supported research on sickle cell disease — also called sickle cell anemia — since before the NHLBI’s founding in 1948 With each passing decade, the NHLBI has kept a focus on advancing the understanding of sickle cell disease and improving clinical care for people who have it





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