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  • The fate of surplus laboratory animals: - EMBO reports
    Many other surplus animals arise from scientific or commercial stock and maintenance breeding to enable animal testing in a timely manner As many research projects are carried out under time pressure and or with time‐limited funding, breeders maintain a large stock of animals with diverse genetic backgrounds so as to quickly satisfy demand or to generate the required genetic combinations
  • 10 million animals are hit on our roads each year. Here’s how . . .
    Every year people crash their vehicles hitting, or trying to avoid hitting, animals on the road, with 5% of fatal accidents caused by collisions with animals Of those, 42% tried to swerve to
  • Editorial policies - Research Involving Human and-or animal . . .
    When reporting a study that involved human participants, their data or biological material, authors should include a statement that confirms that the study was approved (or granted exemption) by the appropriate institutional and or national research ethics committee (including the name of the ethics committee) and certify that the study was performed in accordance with the ethical standards as
  • Suffering for Science and How Science Supports the End of . . .
    Over the past few decades, “evidence-based medicine” has become the mantra of sound, scientifically-based medical research and practice We rely on evidence-based medicine in virtually every facet of health research, ethics, and practice, save one—the use of animal experimentation to inform human health
  • Animal testing on non-human primates - Wikipedia
    Fortrea primate-testing lab, Vienna, Virginia, 2004–05 Most of the NHPs used are one of three species of macaques, accounting for 79% of all primates used in research in the UK, and 63% of all federally funded research grants for projects using primates in the U S [25] Lesser numbers of marmosets, tamarins, spider monkeys, owl monkeys, vervet monkeys, squirrel monkeys, and baboons are used
  • Bioethics and Animal Use in Programs of Research, Teaching . . .
    The use of nonhuman animals (hereinafter “animals”) for the benefit of humans and other animals is a contentious subject throughout many of the world’s countries Cultural morals and traditions, the status of animals in various religions, individual and cultural ethical values, and the diversity of concern for specific species (including the perceptions about the “warm and fuzzies
  • Pharmaceutical toxicology: Designing studies to reduce animal . . .
    Additionally, the European Medical Agency (EMA) recognized the increased use of in vitro methods with a recent revision of their concept paper on the replacement of animal studies with in vitro tests (EMA, 2012) One purpose of this paper was to more clearly define the process for regulatory acceptance of alternatives, including the need for
  • How many species are there? - Our World in Data
    In 2022, it listed 2 16 million species on the planet In the chart, we see the breakdown across a range of taxonomic groups — 1 05 million insects, over 11,000 birds, over 11,000 reptiles, and over 6,000 mammals
  • The US Just Greenlit High-Tech Alternatives to Animal Testing
    A 2021 study calculated that annual figure at more than 111 million mice and rats, which make up the vast majority of lab animals But that study was criticized for extrapolating national numbers
  • The chicken embryo as an in vivo experimental model for drug . . .
    Lab Animal - Alternatives for in vivo assays for drug testing have been proposed to solve open issues, such as costs, ethical, and logistical problems One option is the chicken embryo Here, we
  • Importance of Systematic Reviews and Meta-analyses of Animal . . .
    Systematic reviews and meta-analyses of animal data are important tools to condense animal evidence and translate the data into practical clinical applications Such studies are conducted to explore heterogeneity, to generate new hypotheses about pathophysiology and treatment, to design new clinical trial modalities, and to test the efficacy
  • Stray Animal Population Control: Methods, Public Health . . .
    It has been estimated that approximately 7 6 million pet animals enter into stray every year, of which about 3 4 million are cats (Statistics - National Kitten Coalition, 2020) According to the World Health Organization (WHO), the estimated number of stray dogs was approximately 200 million or more worldwide between 2009 and 2010 (Patti, 2011)
  • Animal Morality: What It Means and Why It Matters - PMC
    For example, Purves and Delon have recently given an account of how animals’ lives can be meaningful that could be used to argue that a life in which an animal is allowed to exercise her moral subjecthood is more meaningful to her, and thus better 15 The integrity approach defended by Rutgers and Heeger could also be extended to argue that a
  • Animal Models to Test SARS-CoV-2 Vaccines: Which Ones Are in . . .
    In large animal models, replicating the pathogenesis of human diseases is easier, because they are physiologically, immunologically, and genetically more closely related, but there are high costs and resources involved, which limit the number of animals that can be included in a study, and there is wide variability in genetic backgrounds [17,18
  • in Vivo Studies - an overview | ScienceDirect Topics
    4 4 In vitro studies The so-called in vivo studies, referring to experimentation using a whole, living organism, are often substituted preceded by low-cost in vitro experiments This type of research aims at describing the effects of experimental variables on the organism's constituent parts (e g , organs, tissue- or cell cultures, cellular





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