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  • What are the symptoms of Down syndrome? - NICHD
    Decreased or poor muscle tone; Short neck, with excess skin at the back of the neck; Flattened facial profile and nose; Small head, ears, and mouth; Upward slanting eyes, often with a skin fold that comes out from the upper eyelid and covers the inner corner of the eye; White spots on the colored part of the eye (called Brushfield spots)
  • Prader-Willi Syndrome (PWS) - NICHD - Eunice Kennedy Shriver National . . .
    Before age 3, the most important symptom is extremely poor muscle tone, called hypotonia, which makes infants feel floppy In affected children 3 years of age and older, other symptoms become apparent, such as obesity, intellectual delays, learning disabilities, or behavior problems, especially connected with food and eating 3
  • What are the symptoms of Prader-Willi syndrome (PWS)?
    "Floppiness" and poor muscle tone; Weak cries and a weak sucking reflex; Inability to breastfeed, which may require feeding support, such as tube feeding; Developmental delays; Small genital organs; Stage 2 (Ages 2 to 8) Unable to feel satisfied with normal intake of food; Inability to control eating, which can lead to overeating if not monitored
  • What conditions or disorders are commonly associated with Down syndrome . . .
    Hypotonia (poor muscle tone) Poor muscle tone and low strength contribute to the delays in rolling over, sitting up, crawling, and walking that are common in children with Down syndrome Despite these delays, children with Down syndrome can learn to participate in physical activities like other children 6
  • Down Syndrome - NICHD - Eunice Kennedy Shriver National Institute of . . .
    Hypotonia (poor muscle tone) Poor muscle tone and low strength contribute to the delays in rolling over, sitting up, crawling, and walking that are common in children with Down syndrome Despite these delays, children with Down syndrome can learn to participate in physical activities like other children 6
  • Urinary Tract Health - NICHD - Eunice Kennedy Shriver National . . .
    Older women with UTIs are more likely to feel tired, shaky, and weak and have muscle aches and abdominal pain 1 In some older women, a UTI can quickly lead to a serious whole-body infection called sepsis Sometimes the progression to sepsis can occur without a fever, so it is important that older women with UTI receive timely initial and
  • How do healthcare providers diagnose Prader-Willi syndrome (PWS)?
    In many cases of Prader-Willi syndrome, diagnosis is prompted by physical symptoms in the newborn If a newborn is unable to suck or feed for a few days and has a "floppy" body and weak muscle tone, a health care provider may conduct genetic testing for Prader-Willi syndrome 1,2,3 Formal diagnostic criteria for recognizing Prader-Willi syndrome depend on the age of the individual-specifically
  • Cerebral Palsy - NICHD - Eunice Kennedy Shriver National Institute of . . .
    Muscle tone; Control of movement; Hearing and vision; Posture; Coordination and balance; If a health care provider finds signs of cerebral palsy during an examination, he or she may then use one or more brain scanning methods to look for damage in the brain These methods may include 1,2: Ultrasound This method is used most commonly in high


















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