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How Does Cystic Fibrosis (CF) Cause Nasal Polyps?
If surgery is required, patients report that it greatly improves headaches, congestion, and runny nose One study found that people with CF had fewer hospital stays in the first six months after sinus surgery 4 Some researchers believe that cystic fibrosis-related nasal polyps are different from nasal polyps caused by other health conditions 5
Nasal Polyps in Cystic Fibrosis Patients: Causes, Symptoms, and . . .
Treatment for nasal polyps in cystic fibrosis patients aims to alleviate symptoms, reduce inflammation, and prevent recurrence The approach depends on the severity of the condition and the patient’s overall health 1 Medications Intranasal Corticosteroids: These are the first-line treatment for nasal polyps They help reduce inflammation and shrink polyps, improving nasal airflow Common options include fluticasone and mometasone
Etiology of Nasal Polyps in Cystic Fibrosis: Not a Unimodal Disease
Agents capable of reducing extracellular DNA may help manage sinusitis in CF patients Keywords: cystic fibrosis, DNA, eosinophil, histology, mucolytic, nasal polyp, neutrophil Tos M, Mogensen C, Thomsen J Nasal polyps in cystic fibrosis J Laryngol Otol 1977;91:827–35 doi: 10 1017 s0022215100084449 [Google Scholar] 10 Harlin SL, Ansel DG, Lane SR, Myers J, Kephart GM, Gleich GJ A clinical and pathologic study of chronic sinusitis: the role of the eosinophil
Nasal Polyps in Cystic Fibrosis - CHEST
Nasal polyps frequently appear in patients with cystic fibrosis (CF) The aims of this study were to focus on what problems (symptoms, endoscopic findings, and laboratory correlates) nasal polyps cause the CF patient, and how these correlate to the total health situation of this patient group
Sinonasal Manifestations of Cystic Fibrosis - Medscape
The investigators found that in patients with cystic fibrosis who had nasal polyps and the poorest baseline scores on the QOD, the drug combination led to clinically significant change In patients with better baseline QOD scores, however, the treatment tended to produce qualitative score improvements that were nonetheless not clinically
Pathogenesis and Management of Nasal Polyposis in Cystic Fibrosis
Beginning in preschool age, during their lives, up to 50% of cystic fibrosis (CF) patients experience obstructing nasal polyposis (NP), which is rare in non-CF children Pathogenetic factors of NP in general and especially in CF are still obscure However, defective epithelial ion transport from mucosal glands plays a central role in CF, and viscous secretions impair mucociliary clearance, promoting chronic pathogen colonization and neutrophil-dominated chronic inflammation Presently, CF-NP
Chronic rhinosinusitis and nasal polyposis in cystic fibrosis: update . . .
Although cystic fibrosis (CF) is an irreversible genetic disease, advances in treatment have increased the life expectancy of CF patients Upper airway involvement, which is mainly due to pathological changes in the paranasal sinuses, is prevalent in CF patients, although many are only mildly symptomatic (with few symptoms)
Treatment and Prognosis of Nasal Polyps in Cystic Fibrosis
Simple polypectomy was an adequate procedure for patients with substantial nasal symptoms There were no visual complications Other surgical complications were rare Children and adolescents with nasal polyps should have sweat tests by pilocarpine iontophoresis to rule out cystic fibrosis (Am J Dis Child 1982;136:1067-1070)