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  • Lurbinectedin - NCI - National Cancer Institute
    Lurbinectedin is approved to treat: Small cell lung cancer that is metastatic It is used in adults whose disease has gotten worse during or after treatment with platinum chemotherapy This use is approved under FDA’s Accelerated Approval Program
  • Frequently Asked Questions (FAQ) | ZEPZELCA® (lurbinectedin)
    ZEPZELCA ® (lurbinectedin) is a prescription medicine used to treat adults with a kind of lung cancer called small cell lung cancer (SCLC) ZEPZELCA may be used when your lung cancer: has spread to other parts of the body (metastatic), and
  • Lurbinectedin (Zepzelca®) for Small Cell Lung Cancer - ChemoExperts
    How does lurbinectedin (Zepzelca®) work? Lurbinectedin is designed to bind to and damage the DNA of the cancer cells which can kill them or slow their growth Lurbinectedin is given to shrink tumors and help decrease symptoms of small-cell lung cancer but is not commonly given with the goal of cure
  • Lurbinectedin Uses, Side Effects Warnings - Drugs. com
    Lurbinectedin is used to treat small cell lung cancer that has spread to other parts of the body (metastatic) Lurbinectedin is given after a platinum cancer medicine did not work or has stopped working Lurbinectedin may also be used for purposes not listed in this medication guide
  • Lurbinectedin: Side Effects, Uses, Dosage, Interactions, Warnings - RxList
    What Is Lurbinectedin and How Does It Work? Lurbinectedin is a prescription medicine used for the treatment of metastatic small-cell lung cancer in patients with disease progression on or after platinum-based chemotherapy
  • Lurbinectedin (intravenous route) - Mayo Clinic
    Lurbinectedin injection is used to treat metastatic (cancer that has already spread) small cell lung cancer (SCLC) in patients who have received other cancer medicines (eg, platinum-based chemotherapy) that did not work well This medicine is to be given only by or under the direct supervision of your doctor
  • What Is Lurbinectedin? - iCliniq
    Lurbinectedin injection is prescribed and used to treat small cell lung cancer that has metastasized or spread and showing no improvement during and after platinum chemotherapy Lurbinectedin is an alkylating agent that inhibits the active transcription genes
  • Zepzelca (lurbinectedin): Uses, Side Effects, Dosage Reviews - GoodRx
    Zepzelca (lurbinectedin) is a chemotherapy medication that’s used to treat metastatic small cell lung cancer (SCLC) after platinum-based therapies no longer work It’s given as an infusion through the vein once every 3 weeks, so it can be a convenient option This medication often causes side effects like nausea, fatigue, and low blood cell counts
  • Lurbinectedin: Enhancing Immunotherapy Efficacy in Small Cell Lung Cancer
    Lurbinectedin works by inducing DNA damage in cancer cells, leading to the formation of micronuclei This process triggers the activation of the cGAS-STING pathway, a critical component of the innate immune response, leading to the production of type 1 interferons and pro-inflammatory chemokines
  • Unveiling the Mechanism of Lurbinectedin’s Action and Its Potential in . . .
    Lurbinectedin is a selective inhibitor of oncogenic transcription approved for the treatment of adult patients with metastatic small cell lung cancer with disease progression on or after platinum-based chemotherapy





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