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  • TISCH
    Welcome to TISCH2 190 datasets 6,297,320 cells Tumor Immune Single-cell Hub 2 (TISCH2) is a scRNA-seq database focusing on tumor microenvironment (TME) TISCH2 provides detailed cell-type annotation at the single-cell level, enabling the exploration of TME across different cancer types
  • TISCH
    Dataset Browser Search by the datasets For a single dataset, TISCH2 provides meta information, cell-type annotation, expression visualization, differential gene expression, GSEA results, transcription regulator analyses result, and cell-cell interaction results For multiple datasets, TISCH2 provides gene expression comparison
  • TISCH
    Gene Exploration Search a gene across cancer types For a single gene, TISCH2 supports exploring its expression level across different datasets or cancer types, co-expressed genes, and the clinical effect We recommend users to choose several specific cancer types rather than all cancer types for a quick response
  • TISCH
    Tumor Immune Single-cell Hub 2 (TISCH2) is a scRNA-seq database, which aims to characterize tumor microenvironment at single-cell resolution Data collection and processing We collected tumor-related scRNA-seq studies from human and mouse Besides datasets of treatment-naive patients, those with samples treated are also included For each collected dataset, a uniform analysis pipeline
  • TISCH
    TISCHHome Dataset Gene Documentation Statistics TISCH1
  • TISCH
    For the ICB dataset, TISCH provides ten ICB-associated signatures collected from published papers Users can select interesting signatures to explore the expression at the cell and cell type levels
  • TISCH
    Cluster Celltype (malignancy) Celltype (major-lineage) Celltype (minor-lineage) Gene Log2 FC Percentage (%) Adjusted p-value Individual gene exploration Search Gene signature exploration





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