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  • Adrenoleukodystrophy - Wikipedia
    Adrenoleukodystrophy (ALD) is a disease linked to the X chromosome It is a result of fatty acid buildup caused by failure of peroxisomal fatty acid beta oxidation which results in the accumulation of very long chain fatty acids in tissues throughout the body
  • Adrenoleukodystrophy (ALD): Causes, Types, Symptoms, Prognosis - WebMD
    About 1 in 17,000 people are born with a genetic disease called adrenoleukodystrophy (ALD) This severe brain disorder mainly affects boys and men There’s no cure yet for it, but a diagnosis
  • Adrenoleukodystrophy (ALD) - Johns Hopkins Medicine
    What is ALD? Adrenoleukodystrophy (ALD) is a genetic condition that damages the membrane (myelin sheath) that covers nerve cells in the brain and spinal cord Myelin acts as insulation around the nerve fibers
  • Adrenoleukodystrophy - Symptoms and causes - Mayo Clinic
    In adrenoleukodystrophy (ALD), your body can't break down very long-chain fatty acids (VLCFAs), causing saturated VLCFA s to build up in your brain, nervous system and adrenal gland The most common type of ALD is X-linked ALD, which is caused by a genetic defect on the X chromosome
  • ALD: Adrenoleukodystrophy, Disease, X-Linked - Cleveland Clinic
    Adrenoleukodystrophy (ALD) is a genetic disorder It affects the nervous system and adrenal glands ALD symptoms include behavioral changes
  • Adrenoleukodystrophy - United Leukodystrophy Foundation
    There are a wide range of clinical severities of X-linked adrenoleukodystrophy (X-ALD), and these have been classified into six broad categories: childhood cerebral ALD, adolescent cerebral ALD, adult cerebral, adrenomyeloneuropathy, adrenal insufficiency-only, and symptomatic heterozygotes
  • Adrenoleukodystrophy - StatPearls - NCBI Bookshelf
    Adrenoleukodystrophy is a rare genetic peroxisomal disorder characterized by the abnormal metabolism of very long-chain fatty acids (VLCFAs) due to mutations in the ABCD1 gene This leads to the accumulation of VLCFAs, particularly affecting the brain, spinal cord, adrenal glands, and testes
  • Adrenoleukodystrophy (ALD) - Boston Childrens Hospital
    Adrenoleukodystrophy (ALD) is a rare genetic condition that affects males and females differently In childhood, boys are primarily affected Girls are not typically affected, though they may develop symptoms as adults
  • Facts about ALD - Adrenoleukodystrophy
    Adrenoleukodystrophy (ALD) is a genetic disorder that affects the adrenal glands, spinal cord, and the white matter of the brain It is severe and progressive The disorder was first identified in 1923 and was formerly known as Schilder’s disease and sudanophilic leukodystrophy





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